The substitution of more appreciated animal species by animal species of lower commercial value is a common type of meat product adulteration.DNA metabarcoding, the combination of DNA barcoding with next-generation sequencing (NGS), plays an increasing role in food authentication.In the present study, we investigated the applicability of a DNA meta
Inositol trisphosphate and ryanodine receptor signaling distinctly regulate neurite pathfinding in response to engineered micropatterned surfaces.
Micro and nanoscale patterning of surface features and biochemical cues have emerged as tools to precisely direct neurite growth into close proximity with next generation neural prosthesis electrodes.Biophysical cues party favor display stands can exert greater influence on neurite pathfinding compared to the more well studied biochemical cues; yet
Association of systemic comorbidity in diabetic serous macular detachment and comparison of various combination therapies in its management
Manoj Soman,1 Sunil Ganekal,2 Unnikrishnan Nair,1 KGR Nair11Chaithanya Eye Hospital and Research Institute, Trivandrum, Kerala, 2Nayana Superspecialty Eye Hospital and Research Center, Davangere, Karnataka, IndiaBackground: The purpose of this research was to study the association between systemic comorbidity in diabetic serous macular detachment (
Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1
Aims: The short QT syndrome type 1 (SQT1) is linked to hERG channel mutations (e.g., N588K).Drug effects on hERG channel gating kinetics in SQT1-cells have not been investigated.Methods: This study used hiPSC-CMs of a healthy donor and a SQT1-patient carrying the N588K mutation and patch clamp to examine the drug effects on hERG channel gating kine
The Role of Neurophysiological Monitoring during Complex Aneurysm Surgery: Report of Two Cases and Review of the Literature
The surgical treatment of intracranial aneurysms is a routine operation in the neurosurgeon practice.Complex aneurysms are those with morphological irregularities, usually large or giant; magnolia parka thrombosed, partially thrombosed or calcified; with aberrant fundus/neck ratio and near eloquent neurological structures.These cases demand special